The Pacific Northwest National Laboratory (PNNL) and the Environmental Molecular Sciences Laboratory (EMSL) are seeking an exceptional candidate for a Postdoctoral Scientist position focused on the development and application of cutting-edge mass spectrometry imaging (MSI) instrumentation, methods, and bioinformatics to analyze sugars, glycans, and glycoconjugates within biological tissues. This position will emphasize leveraging EMSL’s array of high-resolution mass spectrometry platforms to elucidate complex carbohydrate chemistry with implications for human health and disease pathology.

The selected candidate will play a key role in advancing MSI approaches to enable efficient chemical characterization of the glycome—including soluble sugars, glycoproteins, and complex polysaccharides—at cellular resolution. Furthermore, the postdoctoral scientist will utilize these innovative tools to uncover critical insights into how glycome chemistry influences specific cellular functions and establish molecular relationships between individual glycome classes within intricate biological pathways.

The research will benefit from access to state-of-the-art mass spectrometry and microscopy platforms available at PNNL and EMSL. These resources include MALDI-FTICR, MALDI-timsTOF, MALDI-UHMR, ambient ionization techniques (DESI, nano-DESI), tandem mass spectrometry, ion mobility systems (DTIMS, TWIMS, TIMS, SLIM), and high-performance liquid chromatography systems—all of which can be utilized to support the candidate’s groundbreaking work in glycan imaging.

This is an exciting opportunity to contribute to advancements in carbohydrate and glycan imaging, as well as the broader field of glycoscience, using cutting-edge instrumentation and methodologies

Must have direct experience and expertise in at least one field related to glycobiology, biochemistry of carbohydrates, and analytical chemistry of carbohydrates.

LISTING: https://careers.pnnl.gov/jobs/10838?lang=en-us